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جامعة عمّار ثليجي – الأغواط
Université Amar Telidji de Laghouat
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Item type:Item, Prévalence de l'anémie chez les patients hémodialysés au centre d'hémodialyse Pr Sehiri Kamel de L'EPH de Laghouat(université ammar telidji laghouat ,Faculty of Medicine, 2025) BENARFA Hibat Allah; ABIDI ImaneThis prospective study was conducted over a period of six months at the Pr Sehiri Kamel Hemodialysis Center of Laghouat Hospital and focused on the prevalence and management of anemia in chronic hemodialysis patients. The study included 70 patients undergoing regular chronic hemodialysis sessions. Epidemiological data showed that hypertension was the leading cause of end-stage chronic kidney disease, accounting for 36% of cases, followed by undetermined causes in 34% of patients. From a biological perspective, the study revealed that anemia was predominantly normocytic in 84.29% of patients (MCV between 82 and 98 fl) and normochromic in 92.86% of cases (MCHC between 32 and 37 g/dL), which is consistent with the classical characteristics of anemia associated with chronic kidney disease. Follow-up results showed slight fluctuations in mean hemoglobin levels around 10.3 g/dL at study onset, ranging between 10.17 and 10.95 g/dL over six months of follow-up. Despite ongoing treatment, hemoglobin values remained below the recommended therapeutic targets for hemodialysis patients (target Hb 10–12 g/dL according to KDIGO guidelines), highlighting the difficulty of achieving complete correction of anemia in this population. Clinically, the most frequently observed symptoms were asthenia (82%), weight loss (62%), and anorexia (21.42%), reflecting the significant impact of anemia on patients' quality of life. Therapeutic evaluation showed that most patients received treatment based on erythropoiesis-stimulating agents (EPO alpha: 82.86%, darbepoetin: 17.14%), iron supplementation, and vitamin therapy including vitamins B9 and B12. However, therapeutic response remained variable among patients due to several associated factors such as chronic inflammation, iron metabolism disorders, repeated blood loss during hemodialysis sessions, and associated comorbidities. This study highlights the high prevalence of anemia among chronic hemodialysis patients and emphasizes the importance of regular biological monitoring and individualized multidisciplinary management. Optimizing anemia treatment remains essential to improve quality of life, cardiovascular prognosis, and survival in chronic kidney disease patients undergoing hemodialysis.Item type:Item, Real-World Use of Biologic and Targeted Therapies in Internal Medicine: An Ambispective Study at Laghouat Mixed Hospital(2025) BOUCHAREB AHLEM; SAYEH BENAISSA HADJER; CHENINI FATIMA ZAHRBased on the findings of our study, several recommendations may be proposed in order to optimize the use of biologic and targeted therapies in Internal Medicine practice in Algeria. First, strengthening early diagnosis and referral pathways for chronic inflammatory and autoimmune diseases appears essential in order to improve timely access to biologic therapies. Delayed diagnosis and therapeutic escalation may contribute to disease progression, irreversible organ damage, and poorer functional outcomes. Second, systematic pre-therapeutic evaluation should be reinforced before initiation of biologic therapy, particularly regarding infectious screening for tuberculosis, hepatitis B and C, HIV infection, and vaccinationstatus. Given the infectious risks associated with immunosuppressive therapies, standardized screening protocols and close monitoring strategies remain fundamental.Item type:Item, The prevalence of metabolic syndrome among patients with chronic obstructive pulmonary disease(université ammar telidji laghouat ,Faculty of Medicine, 2025) BeromanNihal Mariane; Nafti Rania DalilaTheme: Prevalence of metabolic syndrome among patients with chronic obstructive pulmonary disease (COPD) in the region of Laghouat. Authors: Nafti Rania Dalila / Beroman Nihal Mariane Key words: COPD, metabolic syndrome, prevalence, comorbidities, exacerbations. Objectives: ü To determine the prevalence of metabolic syndrome among patients with COPD; ü To assess the association between metabolic syndrome and COPD severity; ü To identify and describe the main comorbidities associated with COPD. Materials and Methods: This is a cross-sectional descriptive and analytical study conducted over a period of seven months, from july 2025 to April 2026, in the pulmonology department of Colonel Lotfi Hospital in Laghouat. The study included 18 patients diagnosed with COPD according to GOLD 2024 criteria. Metabolic syndrome was defined based on harmonized criteria, requiring the presence of at least three metabolic abnormalities. Clinical, functional, and biological data were collected using a standardized data collection form. Statistical analysis was performed using SPSS and Sourcetable software, with a significance level set at p < 0.05. Results: The prevalence of metabolic syndrome was 44.4% (8 out of 18 patients). The most frequent comorbidities were hypertension (9/18), heart disease (8/18), and diabetes mellitus (4/18). No significant association was found between metabolic syndrome and airflow limitation severity (FEV₁ or GOLD stage). However, metabolic syndrome was significantly associated with dyspnea severity (p = 0.002), exacerbations (p = 0.001), and hospitalization (p = 0.015).Item type:Item, Retentissement du travail de nuit chez le personnel paramédical de l’Hôpital mixte de 240 lits - Laghouat(2025) Benghouini Anouar; Hachachena Samaharam; Hassen Radjaa MaramNight work is essential for maintaining continuity of hospital care, but it exposes paramedical staff to significant biological, physical, and psychological constraints. Night shifts may disrupt the sleep–wake rhythm, impair recovery, increase occupational fatigue, and affect psychological well-being. This study aimed to assess the impact of night work on sleep quality, physical condition, and psychological status among paramedical staff at the 240-bed Ali Ben Deghine Mixed Hospital in Laghouat. Materials and methods: A descriptive cross-sectional study with an analytical component was conducted from October 2025 to May 2026 among 83 paramedical professionals working night shifts. Data were collected using a structured questionnaire. Sleep quality was assessed using the Pittsburgh Sleep Quality Index, psychological status using the DASS-21, and occupational fatigue and recovery using the Mini-OFER. Statistical analysis included descriptive analysis and exploration of associations between night work characteristics and the main health indicators. Results: The mean age of participants was 30.41 ± 8.37 years, with a male predominance of 83.1%. Nurses represented 50.6% of the sample and nursing assistants 47.0%. The mean number of shifts was 8.19 ± 2.09 per month. Sixteen-hour shifts were reported by 78.3% of participants, while 24-hour shifts concerned 21.7%. Poor sleep quality was found in 85.5% of participants, with a mean PSQI score of 8.63 ± 3.25. Regarding psychological status, at least mild anxiety was reported by 60.2% of participants, stress by 54.2%, and depressive symptoms by 44.6%. The mean global Mini-OFER score was 14.07 ± 5.57. Shift duration was significantly associated with the global Mini-OFER score, with p = 0.042. Conclusion: Night work among paramedical staff at the 240-bed Ali Ben Deghine Mixed Hospital in Laghouat is associated with poor sleep quality, notable psychological burden, and marked occupational fatigue. Prolonged shifts, particularly 24-hour shifts, appear to contribute to greater physical impact. These findings highlight the need to strengthen preventive measures, including shift organization, post-shift rest, sleep hygiene, fatigue screening, and occupational health follow-up for night workers.Item type:Item,